Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557522 | 0.98 | MAOA (0.58) | MAOAMAOBNR1H2PTGIRKMT2A | |
| SCHEMBL23639396 | 0.98 | MAOA (0.58) | MAOAMAOBNR1H2PTGIRKMT2A | |
| SCHEMBL9406360 | 0.91 | NR1H2 (0.48) | MAOAMAOBNR1H2KMT2ANPC1 | |
| SCHEMBL11554712 | 0.91 | NR1H2 (0.48) | MAOAMAOBNR1H2KMT2ANPC1 | |
| SCHEMBL23295277 | 0.88 | MAOA (0.65) | MAOAMAOBPTGIRKMT2AAR | |
| SCHEMBL21578967 | 0.82 | MAOA (0.47) | MAOAMAOBNR1H2PTGIRKMT2A | |
| SCHEMBL23639371 | 0.82 | MAOA (0.47) | MAOAMAOBNR1H2PTGIRKMT2A | |
| SCHEMBL14082415 | 0.81 | MAOA (0.42) | MAOAMAOBNR1H2PTGIRKMT2A | |
| SCHEMBL21578834 | 0.79 | MAOA (0.41) | MAOAMAOBNR1H2PTGIRAR | |
| SCHEMBL14082390 | 0.78 | CARM1 (0.43) | MAOAMAOBNR1H2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143076-A | MERCAPTO PHENOLIC AND ALKYLTHIO PHENOLIC ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4128530-A | Mercapto phenolic and alkylthio phenolic antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-12-05 | — | — | US | disclosed |