SCHEMBL1155787

SCHEMBL1155787

c1ccc(-c2ccnn2-c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.55
POLB P06746 1/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
HTT P42858 1/20 0.55
MAPK9 P45984 2/20 0.54
MAPK10 P53779 2/20 0.54
MAPK8 P45983 1/20 0.53
NR3C2 P08235 1/20 0.50
PTGS2 P35354 2/20 0.49
KDM5A P29375 1/20 0.49
KDM4C Q9H3R0 1/20 0.49
KDM5B Q9UGL1 1/20 0.49
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
MAPK14 Q16539 1/20 0.45
RPA1 P27694 1/20 0.44
PTGS1 P23219 1/20 0.44
PDE10A Q9Y233 1/20 0.43
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5907310 0.92 MAPK9 (0.56) MDM2POLBALDH1A1LMNAHTT
SCHEMBL27315071 0.90 MAPK9 (0.68) MDM2POLBALDH1A1LMNAHTT
SCHEMBL28004022 0.87 MAPK9 (0.54) MDM2POLBALDH1A1LMNAHTT
SCHEMBL27310701 0.87 MEN1 (0.51) MDM2POLBALDH1A1LMNAHTT
SCHEMBL15503778 0.87 KDM5A (0.51) MDM2POLBALDH1A1LMNAHTT
SCHEMBL12759885 0.87 MDM2 (0.52) MDM2ALDH1A1LMNAHTTMAPK9
SCHEMBL27742800 0.87 MAPK9 (0.51) MDM2POLBALDH1A1LMNAHTT
SCHEMBL19240299 0.87 POLB (0.52) MDM2POLBALDH1A1LMNAHTT
SCHEMBL17086633 0.87 MDM2 (0.52) MDM2POLBALDH1A1MAPK9MAPK10
SCHEMBL3072066 0.87 MEN1 (0.53) MDM2POLBALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106831584-B A kind of efficient method for preparing tri- substituted pyrazolecarboxylic class compound of 1,3,5- 江西师范大学 2019-11-22 CN claimed
EP-3947350-B1 SUBSTITUTED 2-HETEROARYL AMINOBENZENES, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS BAYER AG (DE) 2026-05-27 EP disclosed
EP-4680598-A1 4-DIFLUOROMETHYL BENZAMIDES WITH HERBICIDAL ACTION Bayer Aktiengesellschaft (DE) 2026-01-21 EP disclosed
WO-2025224076-A1 SUBSTITUTED ARYLPYRAZINES AND SALTS THEREOF, AND USE THEREOF AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-10-30 WO disclosed
EP-4602036-A1 SUBSTITUTED N-PHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2025-08-20 EP disclosed
WO-2025132148-A1 ADJUVANT COMPOSITIONS FOR AGROCHEMICAL APPLICATIONS BAYER AKTIENGESELLSCHAFT (DE) 2025-06-26 WO disclosed
WO-2025108865-A1 HERBICIDAL COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2025-05-30 WO disclosed
WO-2025103927-A1 SUBSTITUTED OXYIMINOMETHYLPHENYL URACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed
WO-2025103931-A1 SUBSTITUTED CYCLOPROPYLOXYPHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed
WO-2025103939-A1 SULFONIMIDOYL BENZAMIDES WITH HERBICIDAL ACTION BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed
US-5380869-A Regioselective synthesis of 1,5-diaryl pyrazole anti-inflammatory agents ORTHO PHARMACEUTICAL CORPORATION (US) 1995-01-10 US disclosed
US-5260458-A 2-oxo tetrahydrofuran compounds ORTHO PHARMACEUTICAL CORPORATION (US) 1993-11-09 US disclosed
EP-0534800-A2 Regioselective synthesis of 1,5-diaryl pyrazole anti-inflammatory agents ORTHO PHARMACEUTICAL CORPORATION (US) 1993-03-31 EP disclosed
US-5117054-A Chemical intermediate for antiinflammatory agents ORTHO PHARMACEUTICAL CORPORATION (US) 1992-05-26 US disclosed
US-4898952-A Regioselective synthesis of a 1,5-disubstituted pyrazole ORTHO PHARMACEUTICAL CORPORATION (US) 1990-02-06 US disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
EP-0293221-A2 Regioselective Synthesis of 1,5-Disubstituted Pyrazoles ORTHO PHARMACEUTICAL CORPORATION (US) 1988-11-30 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed