Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 7/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297197 | 0.85 | MAP2 (0.48) | MAP2CA1CA2LMNASMN1; SMN2 | |
| SCHEMBL11298462 | 0.84 | MAP2 (0.52) | MAP2CA1CA2LMNASMN1; SMN2 | |
| SCHEMBL11304764 | 0.83 | MAP2 (0.42) | MAP2CA1CA2 | |
| SCHEMBL11309419 | 0.83 | MAP2 (0.44) | MAP2CA1CA2LMNASMN1; SMN2 | |
| SCHEMBL11248598 | 0.82 | MCL1 (0.35) | MAP2MCL1 | |
| SCHEMBL11558034 | 0.81 | MAP2 (0.46) | MAP2CA1CA2LMNASMN1; SMN2 | |
| SCHEMBL11255035 | 0.80 | CSF1R (0.34) | MAP2MCL1SMN1; SMN2 | |
| SCHEMBL11298434 | 0.80 | ALDH1A1 (0.51) | MAP2 | |
| SCHEMBL11255700 | 0.80 | MCL1 (0.33) | MAP2CA1CA2MCL1GSK3B | |
| SCHEMBL11251572 | 0.80 | MCL1 (0.32) | MAP2MCL1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000972-A2 | 2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-03-07 | — | — | EP | disclosed |