Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11555475 | 0.98 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL11689282 | 0.90 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL21246048 | 0.87 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7487086 | 0.86 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL11505491 | 0.83 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL11660383 | 0.83 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL11655066 | 0.83 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL11656877 | 0.83 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL11656014 | 0.80 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B | |
| SCHEMBL9040161 | 0.80 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139634-A | ANTIDEPRESSANTS, ANTIAGGRESSION AGENTS, ANESTHETICS | LABAZ (FR) | 1979-02-13 | — | — | US | disclosed |