Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532469 | 0.84 | HTR2C (0.54) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL6425272 | 0.83 | HTR2C (0.52) | HTR2CHTR2BHTR2A | |
| SCHEMBL19137413 | 0.77 | ADRA1B (0.42) | SMN1; SMN2ADRA1BLMNAALDH1A1NOTUM | |
| SCHEMBL27240579 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2HTR2CHTR2BLMNAALDH1A1 | |
| SCHEMBL23911866 | 0.72 | NOTUM (0.40) | SMN1; SMN2ADRA1BLMNAALDH1A1NOTUM | |
| SCHEMBL7537388 | 0.71 | MEN1 (0.49) | SMN1; SMN2HTR2CHTR2BADRA1BALDH1A1 | |
| SCHEMBL22270895 | 0.71 | AAK1 (0.42) | SMN1; SMN2ADRA1BLMNAGAAHTT | |
| SCHEMBL693081 | 0.69 | HTR2C (0.58) | HTR2CHTR2BHTR2A | |
| SCHEMBL2018190 | 0.69 | HTR2C (0.58) | HTR2CHTR2BHTR2A | |
| SCHEMBL692326 | 0.69 | HTR2C (0.58) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |