Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661063 | 0.83 | PTGS1 (0.41) | PTGS1HTR7GPBAR1NPC1RAB9A | |
| SCHEMBL11560907 | 0.82 | PTGS1 (0.43) | PTGS1HTR7GPBAR1NPC1RAB9A | |
| SCHEMBL10657148 | 0.80 | PTGS1 (0.41) | PTGS1HTR7GPBAR1NPC1RAB9A | |
| SCHEMBL11557039 | 0.79 | PTGS1 (0.43) | PTGS1HTR7GPBAR1NPC1RAB9A | |
| SCHEMBL11559146 | 0.76 | NPC1 (0.44) | PTGS1HTR7GPBAR1NPC1RAB9A | |
| SCHEMBL10730942 | 0.76 | PTGS1 (0.36) | PTGS1HTR7GPBAR1RAB9AMAPK1 | |
| SCHEMBL10655898 | 0.76 | KMT2A (0.38) | PTGS1GPBAR1NPC1RAB9AMAPK1 | |
| SCHEMBL11558673 | 0.75 | PTGS1 (0.45) | PTGS1HTR7GPBAR1NPC1RAB9A | |
| SCHEMBL10729133 | 0.75 | PTGS1 (0.36) | PTGS1HTR7GPBAR1MAPK1HPGD | |
| SCHEMBL11558759 | 0.72 | NPC1 (0.46) | PTGS1HTR7GPBAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002666-A1 | 1,2-Benzisoxazolyloxy (or thio) acetic acids and related compounds, process for their preparation and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |