Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559072 | 0.82 | PTGS1 (0.44) | PTGS1NPC1RAB9AHTR7GPBAR1 | |
| SCHEMBL11559146 | 0.81 | NPC1 (0.44) | PTGS1NPC1RAB9AHTR7GPBAR1 | |
| SCHEMBL11558673 | 0.80 | PTGS1 (0.45) | PTGS1NPC1RAB9AHTR7GPBAR1 | |
| SCHEMBL11557039 | 0.78 | PTGS1 (0.43) | PTGS1NPC1RAB9AHTR7GPBAR1 | |
| SCHEMBL11558759 | 0.77 | NPC1 (0.46) | PTGS1NPC1RAB9AHTR7GPBAR1 | |
| SCHEMBL11258956 | 0.76 | PTGDR2 (0.42) | NPC1RAB9AGPBAR1MAPTTP53 | |
| SCHEMBL10661063 | 0.76 | PTGS1 (0.41) | PTGS1NPC1RAB9AHTR7GPBAR1 | |
| SCHEMBL11557509 | 0.73 | PTGS1 (0.41) | PTGS1NPC1RAB9AHTR7GPBAR1 | |
| SCHEMBL11557665 | 0.73 | PTGS1 (0.41) | PTGS1NPC1RAB9AHTR7GPBAR1 | |
| SCHEMBL10657148 | 0.73 | PTGS1 (0.41) | PTGS1NPC1RAB9AHTR7GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002666-A1 | 1,2-Benzisoxazolyloxy (or thio) acetic acids and related compounds, process for their preparation and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |