Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560053 | 0.89 | MAPT (0.53) | MAPTRXFP1KMT2AMEN1LMNA | |
| SCHEMBL11559016 | 0.88 | RXFP1 (0.47) | MAPTRXFP1KMT2AMEN1LMNA | |
| SCHEMBL11560728 | 0.83 | MAPT (0.62) | MAPTRXFP1KMT2AMEN1LMNA | |
| SCHEMBL11566445 | 0.83 | CA1 (0.50) | MAPTRXFP1KMT2AMEN1LMNA | |
| SCHEMBL11559120 | 0.82 | RXFP1 (0.46) | MAPTRXFP1KMT2AMEN1LMNA | |
| SCHEMBL11859215 | 0.81 | CA1 (0.50) | MAPTRXFP1KMT2AMEN1POLB | |
| SCHEMBL11567284 | 0.79 | KMT2A (0.49) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL11566691 | 0.79 | CA1 (0.69) | MAPTRXFP1KMT2AMEN1LMNA | |
| SCHEMBL11559522 | 0.78 | CA1 (0.51) | MAPTKMT2AMEN1POLBCA1 | |
| SCHEMBL11560561 | 0.78 | MAPT (0.53) | MAPTRXFP1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165229-A | SUBSTITUTED THIADIAZOL-2-YLUREA | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |