Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566445 | 0.86 | CA1 (0.50) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL11566691 | 0.82 | CA1 (0.69) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL11559522 | 0.81 | CA1 (0.51) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL11560053 | 0.81 | MAPT (0.53) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL11560728 | 0.81 | MAPT (0.62) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL11560223 | 0.80 | CA1 (0.47) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL11559615 | 0.79 | MAPT (0.51) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL11859215 | 0.79 | CA1 (0.50) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL11559016 | 0.78 | RXFP1 (0.47) | KMT2AMEN1CA1CA2CA4 | |
| SCHEMBL11559120 | 0.77 | RXFP1 (0.46) | KMT2AMEN1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165229-A | SUBSTITUTED THIADIAZOL-2-YLUREA | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |