SCHEMBL11560282

SCHEMBL11560282

Cc1cc(Cl)c(C(=O)NC(=O)Nc2ccc(Cl)cc2)c(Cl)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PCTP Q9UKL6 9/20 0.54
STARD10 Q9Y365 5/20 0.51
STARD7 Q9NQZ5 1/20 0.51
RAB9A P51151 5/20 0.48
GBA1 P04062 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
POLB P06746 2/20 0.47
NPC1 O15118 2/20 0.46
HTT P42858 2/20 0.46
LMNA P02545 1/20 0.46
EPHX1 P07099 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CHRM1 P11229 1/20 0.46
SLC6A2 P23975 1/20 0.46
PDE4A P27815 1/20 0.46
EPHX2 P34913 1/20 0.46
ADRA1A P35348 1/20 0.46
OPRM1 P35372 1/20 0.46
PDE3A Q14432 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13235115 0.83 MEN1 (0.65) PCTPSTARD10STARD7RAB9AGBA1
SCHEMBL11562485 0.81 RAB9A (0.51) PCTPRAB9AGBA1MEN1KMT2A
SCHEMBL11557801 0.78 EGFR (0.56) PCTPSTARD10STARD7RAB9AGBA1
SCHEMBL11559575 0.78 MEN1 (0.47) PCTPRAB9AGBA1MEN1KMT2A
SCHEMBL11552850 0.77 MEN1 (0.50) PCTPRAB9AGBA1MEN1KMT2A
SCHEMBL7598432 0.77 RAB9A (0.54) RAB9AGBA1MEN1KMT2ANPC1
SCHEMBL11559964 0.77 RAB9A (0.52) RAB9AMEN1KMT2ANPC1HTT
SCHEMBL11552808 0.75 KMT2A (0.54) RAB9AMEN1KMT2ANPC1HTT
Dichlorbenzuron SCHEMBL3663126 0.74 CNR1 (0.54) RAB9AMEN1KMT2ANPC1HTT
SCHEMBL11560710 0.73 RAB9A (0.46) RAB9AMEN1KMT2ANPC1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4148902-A N-[(optionally substituted phenylamino)carbonyl] pyridine carboxamides and insecticidal use thereof THE DOW CHEMICAL COMPANY (US) 1979-04-10 US claimed