Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560557 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRALDH1A1TP53HIF1A | |
| SCHEMBL11567144 | 0.81 | CHRM1 (0.52) | SMN1; SMN2ALDH1A1CHRNB2CHRNA4CHRM2 | |
| SCHEMBL11567146 | 0.81 | CHRM1 (0.52) | SMN1; SMN2ALDH1A1CHRNB2CHRNA4CHRM2 | |
| SCHEMBL11557485 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRALDH1A1TP53HIF1A | |
| SCHEMBL11563279 | 0.80 | ATM (0.55) | SMN1; SMN2TSHRALDH1A1HSD17B10ATM | |
| SCHEMBL11550350 | 0.80 | ATM (0.55) | SMN1; SMN2TSHRALDH1A1HSD17B10ATM | |
| SCHEMBL11550353 | 0.80 | ATM (0.55) | SMN1; SMN2TSHRALDH1A1HSD17B10ATM | |
| SCHEMBL11548834 | 0.79 | NPSR1 (0.50) | TSHRALDH1A1HSD17B10MAPTNPSR1 | |
| SCHEMBL11548836 | 0.79 | NPSR1 (0.50) | TSHRALDH1A1HSD17B10MAPTNPSR1 | |
| SCHEMBL11555877 | 0.79 | NPSR1 (0.50) | TSHRALDH1A1HSD17B10MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162321-A | Sulphur-containing amino-dihydropyridines, and their use as medicants | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |