Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | STK17B | O94768 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560790 | 0.91 | ROCK1 (0.50) | ROCK1KDM4EIDO1CYP2A6MAPT | |
| SCHEMBL11559528 | 0.83 | HPGD (0.37) | ROCK1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL11555309 | 0.81 | KDM4E (0.38) | ROCK1KDM4EMEN1KMT2A | |
| SCHEMBL11558674 | 0.80 | L3MBTL1 (0.42) | SMN1; SMN2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6076483 | 0.80 | ROCK1 (0.72) | ROCK1KDM4EIDO1CYP2A6MAPT | |
| SCHEMBL11557070 | 0.79 | L3MBTL1 (0.40) | ROCK1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL11531911 | 0.78 | PDE10A (0.49) | ROCK1KDM4EIDO1PDE10APIM1 | |
| SCHEMBL11531399 | 0.77 | ROCK1 (0.44) | ROCK1KDM4EIDO1CYP2A6PDE10A | |
| Hydrochloric Acid SCHEMBL11529086 | 0.77 | PDE10A (0.48) | ROCK1KDM4EIDO1PDE10APIM1 | |
| SCHEMBL10745872 | 0.76 | ROCK1 (0.48) | ROCK1KDM4EIDO1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157399-A | Benzo(B)thiophenes | PARCOR (FR) | 1979-06-05 | — | — | US | disclosed |