Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557122 | 0.92 | TP53 (0.45) | TP53NR1I2KMT2ATDP1MEN1 | |
| SCHEMBL11563452 | 0.89 | KDM4E (0.36) | TP53KMT2ATDP1MEN1HPGD | |
| SCHEMBL11561630 | 0.88 | NR1I2 (0.41) | TP53NR1I2KMT2ATDP1MEN1 | |
| SCHEMBL11554505 | 0.87 | TP53 (0.44) | TP53NR1I2KMT2ATDP1MEN1 | |
| SCHEMBL11561213 | 0.87 | TP53 (0.39) | TP53NR1I2KMT2ATDP1MEN1 | |
| SCHEMBL11554270 | 0.87 | TP53 (0.38) | TP53NR1I2KMT2ATDP1MEN1 | |
| SCHEMBL11564840 | 0.86 | NR1I2 (0.39) | TP53NR1I2KMT2ATDP1MEN1 | |
| SCHEMBL11559887 | 0.85 | NR1I2 (0.41) | TP53NR1I2KMT2ATDP1MEN1 | |
| SCHEMBL11560747 | 0.83 | TP53 (0.44) | TP53NR1I2KMT2ATDP1MEN1 | |
| SCHEMBL11560799 | 0.82 | NR1I2 (0.41) | TP53NR1I2KMT2ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |