Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557240 | 0.93 | NR1I2 (0.39) | NR1I2TDP1MEN1KMT2AEGFR | |
| SCHEMBL11561630 | 0.93 | NR1I2 (0.41) | NR1I2TDP1MEN1KMT2AEGFR | |
| SCHEMBL11561755 | 0.91 | MEN1 (0.42) | NR1I2TDP1MEN1KMT2AGRIN2D | |
| SCHEMBL11554270 | 0.89 | TP53 (0.38) | NR1I2TDP1MEN1KMT2AGRIN2D | |
| SCHEMBL11561856 | 0.88 | ESR1 (0.40) | TDP1EGFRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL11560769 | 0.87 | EGFR (0.38) | NR1I2TDP1MEN1KMT2AEGFR | |
| SCHEMBL11564121 | 0.87 | TP53 (0.43) | NR1I2TDP1MEN1KMT2AGRIN2D | |
| SCHEMBL11560799 | 0.86 | NR1I2 (0.41) | NR1I2TDP1MEN1KMT2AEGFR | |
| SCHEMBL11560713 | 0.86 | TP53 (0.41) | NR1I2TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL11559244 | 0.85 | NR1I2 (0.41) | NR1I2TDP1MEN1KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |