Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705085 | 0.72 | POLB (0.62) | POLBCYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL8866026 | 0.72 | POLB (1.00) | POLBCYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL9097244 | 0.72 | POLB (0.55) | POLBCYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL11550446 | 0.71 | POLB (0.57) | POLBCYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL11010710 | 0.70 | POLB (0.60) | POLBCYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL3473120 | 0.70 | POLB (0.60) | POLBCYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL13907297 | 0.70 | CYP11B1 (0.68) | POLBCYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL11555502 | 0.70 | POLB (0.68) | POLBCYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL22871616 | 0.70 | RAB9A (0.44) | MEN1KMT2ASMN1; SMN2CYP1A2MAPT | |
| SCHEMBL13907298 | 0.69 | CYP11B1 (0.63) | POLBCYP19A1CYP11B1CYP11B2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171366-A | 1-Naphthothienylalkyl-1H-imidazoles | CIBA-GEIGY CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |