Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.55 |
| ▸ | CA2 | P00918 | 12/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1925386 | 0.85 | SMN1; SMN2 (0.47) | CA1CA2SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL940787 | 0.85 | STAT3 (0.51) | CA1CA2OPRM1OPRD1MMP2 | |
| SCHEMBL13687243 | 0.83 | SMN1; SMN2 (0.52) | CA1CA2OPRM1OPRD1CA7 | |
| SCHEMBL7143525 | 0.81 | CA1 (0.58) | CA1CA2MMP2CA7CA13 | |
| SCHEMBL8054565 | 0.81 | POLB (0.47) | SMN1; SMN2KDM4ELMNAMAPTHTT | |
| SCHEMBL2776082 | 0.81 | ERN1 (0.43) | CA1CA2SMN1; SMN2CA12 | |
| Alipamide SCHEMBL120853 | 0.80 | CA1 (0.61) | CA1CA2OPRM1OPRD1STAT3 | |
| SCHEMBL11711971 | 0.80 | MEN1 (0.58) | CA1CA2CA7CA13HTT | |
| SCHEMBL31018987 | 0.80 | CA1 (0.59) | CA1CA2MMP2CA7CA13 | |
| SCHEMBL31670541 | 0.80 | CA1 (0.63) | CA1CA2MMP2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190814-B1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS | UNIV JOHNS HOPKINS (US) | 2017-02-01 | — | — | EP | disclosed |
| US-7589207-B2 | Cyclohexyl compounds as CCR5 antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2009-09-15 | — | — | US | disclosed |
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |