Alipamide

Alipamide

SCHEMBL120853

CN(C)NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 16/20 0.61
CA2 P00918 16/20 0.61
OPRM1 P35372 1/20 0.58
OPRD1 P41143 1/20 0.58
STAT3 P40763 2/20 0.55
KDM4E B2RXH2 1/20 0.55
LMNA P02545 1/20 0.55
GLA P06280 1/20 0.55
MAPT P10636 1/20 0.55
HTT P42858 1/20 0.55
HSD17B10 Q99714 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alipamide SCHEMBL28278565 0.99 CA1 (0.60) CA1CA2OPRM1OPRD1STAT3
Alipamide SCHEMBL3793041 0.96 OPRM1 (0.64) CA1CA2OPRM1OPRD1STAT3
Alipamide SCHEMBL3797100 0.96 OPRM1 (0.64) CA1CA2OPRM1OPRD1STAT3
SCHEMBL13687260 0.83 CA1 (0.66) CA1CA2STAT3KDM4ELMNA
SCHEMBL1272484 0.81 CA1 (0.71) CA1CA2
SCHEMBL11560883 0.80 CA1 (0.55) CA1CA2OPRM1OPRD1STAT3
SCHEMBL13687209 0.79 CA1 (0.72) CA1CA2OPRM1OPRD1
SCHEMBL11357962 0.79 CA1 (0.61) CA1CA2
SCHEMBL10829518 0.79 CA1 (0.60) CA1CA2OPRM1OPRD1STAT3
SCHEMBL940024 0.78 MMP2 (0.60) CA1CA2OPRM1OPRD1STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20020115655-A1 Such as S-(4-methoxybenzyl)-N-(2-(N',N'-dimethylamino)ethyl) thiosalicylamide; for treatment of cardiovascular disorders MASSACHUSETTS COLLEGE OF PHARMACY 2002-08-22 US claimed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 US claimed
EP-0032725-B1 NOVEL ALDEHYDE ADDUCTS OF TRIAMTERENE AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME MERCK & CO. INC. (US) 1985-05-08 EP claimed
US-4285947-A DIURETICS, HYPOTENSIVES INTERX RESEARCH CORPORATION (US) 1981-08-25 US claimed
EP-0032725-A1 Novel aldehyde adducts of triamterene and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1981-07-29 EP claimed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 US disclosed
US-12465564-B2 Oral and nasal compositions and methods of treatment AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
US-20250339367-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-06 US disclosed
EP-0032725-B1 NOVEL ALDEHYDE ADDUCTS OF TRIAMTERENE AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME MERCK & CO. INC. (US) 1985-05-08 EP disclosed
EP-0129284-A2 Improved penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one THE PROCTER & GAMBLE COMPANY (US) 1984-12-27 EP disclosed
EP-0129285-A2 Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl)pyrrolidone THE PROCTER & GAMBLE COMPANY (US) 1984-12-27 EP disclosed
US-4285947-A DIURETICS, HYPOTENSIVES INTERX RESEARCH CORPORATION (US) 1981-08-25 US disclosed
EP-0032725-A1 Novel aldehyde adducts of triamterene and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1981-07-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A CA1 245/4885CA2 620/4885OPRM1 1993/4885
US-20020115655-A1 Such as S-(4-methoxybenzyl)-N-(2-(N',N'-dimethylamino)ethyl) thiosalicylamide; for treatment of cardiovascular disorders CACNA1G, CACNA1F, CACNA1H CA1 3067/4885CA2 131/4885OPRM1 1222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.