Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558533 | 0.85 | DPP4 (0.43) | DPP4TSHRHSD11B1FAAHCES2 | |
| SCHEMBL11561222 | 0.83 | DPP4 (0.48) | DPP4LMNATSHRHSD11B1FAAH | |
| SCHEMBL11562959 | 0.82 | LMNA (0.38) | DPP4LMNATSHRFAAHKMT2A | |
| SCHEMBL11561571 | 0.82 | TSHR (0.38) | DPP4LMNATSHRKMT2AMEN1 | |
| SCHEMBL11563939 | 0.81 | TSHR (0.38) | DPP4LMNATSHRKMT2AMEN1 | |
| SCHEMBL11561621 | 0.81 | LMNA (0.37) | DPP4LMNATSHRKMT2AMEN1 | |
| SCHEMBL11561061 | 0.79 | LMNA (0.36) | DPP4LMNATSHRFAAHALDH1A1 | |
| SCHEMBL11564592 | 0.79 | TSHR (0.36) | DPP4LMNATSHRNPSR1ALDH1A1 | |
| SCHEMBL11563670 | 0.79 | DPP4 (0.48) | DPP4LMNATSHRFAAHCES2 | |
| SCHEMBL11566245 | 0.78 | DPP4 (0.35) | DPP4LMNATSHRNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148626-A | Herbicidal agents | THE BOOTS COMPANY LIMITED (GB) | 1979-04-10 | — | — | US | disclosed |