Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560585 | 0.93 | TP53 (0.44) | TP53CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL11561755 | 0.92 | MEN1 (0.42) | TP53CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL11561020 | 0.92 | GRIN2D (0.41) | TP53CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL11560955 | 0.89 | TP53 (0.47) | TP53CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL11561856 | 0.87 | ESR1 (0.40) | TP53CYP3A4ALDH1A1TDP1GRIN2D | |
| SCHEMBL11564840 | 0.87 | NR1I2 (0.39) | TP53CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL11560912 | 0.86 | GRIN2D (0.39) | TP53CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL11554505 | 0.86 | TP53 (0.44) | TP53CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL11563473 | 0.85 | MEN1 (0.42) | TP53CYP3A4ALDH1A1TDP1MEN1 | |
| SCHEMBL11558233 | 0.84 | GRIN2D (0.38) | TP53CYP3A4ALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |