Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564624 | 0.90 | NPSR1 (0.37) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11556631 | 0.87 | TSHR (0.45) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11564619 | 0.86 | TSHR (0.41) | HTTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL11562926 | 0.86 | CYP1A2 (0.33) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11561953 | 0.86 | KDM4E (0.42) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11564223 | 0.86 | NPSR1 (0.42) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11559394 | 0.85 | TSHR (0.40) | SMN1; SMN2KDM4ETSHR | |
| SCHEMBL11564662 | 0.84 | VCAM1 (0.32) | MEN1KMT2A | |
| SCHEMBL11556664 | 0.83 | SMN1; SMN2 (0.43) | LMNAHTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL11558652 | 0.81 | MAPT (0.37) | MAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148626-A | Herbicidal agents | THE BOOTS COMPANY LIMITED (GB) | 1979-04-10 | — | — | US | disclosed |