Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099610 | 0.86 | IDO1 (0.58) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL11582838 | 0.84 | HTR2A (0.50) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL11582840 | 0.84 | HTR2A (0.50) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL11566178 | 0.84 | HTR2A (0.54) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL8247254 | 0.83 | HTR2A (0.60) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL10465292 | 0.80 | MAOB (0.56) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL11562316 | 0.80 | BCL9 (0.51) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL10801173 | 0.79 | HTR2A (0.67) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL11147561 | 0.79 | HTR2A (0.56) | HTR2AHTTRAB9AIDO1ALDH1A1 | |
| SCHEMBL10569487 | 0.79 | ACHE (0.58) | HTR2AHTTRAB9AIDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000636-A1 | Penem compounds, processes for their preparation, their use in pharmaceutical compositions and azetidinones used in their preparation | GLAXO GROUP LIMITED (GB) | 1979-02-07 | — | — | EP | disclosed |