Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPFFR1 | Q9GZQ6 | 3/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566366 | 0.87 | CA12 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11564443 | 0.85 | CA12 (0.59) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11563820 | 0.83 | CA12 (0.47) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11563362 | 0.81 | DRD3 (0.53) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11563591 | 0.80 | CA12 (0.46) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11562772 | 0.80 | OPRM1 (0.54) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11568966 | 0.80 | CA12 (0.57) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11567856 | 0.80 | CA12 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11565608 | 0.79 | CA12 (0.46) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11565960 | 0.79 | OPRM1 (0.47) | CA12CA1CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |