SCHEMBL11564358

SCHEMBL11564358

COP(=O)(OC)O/C=C/Cl

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
LMNA P02545 1/20 0.50
ALOX15 P16050 1/20 0.50
ACHE P22303 1/20 0.50
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9929816 1.00 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRLMNAALOX15
SCHEMBL11598484 0.83
SCHEMBL2179466 0.78 ALDH1A1 (0.48) ALDH1A1CYP3A4TSHRLMNAALOX15
Ammonia Solution, Strong SCHEMBL30983213 0.76 ALDH1A1 (0.46) ALDH1A1CYP3A4TSHRLMNAALOX15
Ammonia Solution, Strong SCHEMBL29058011 0.76 ALDH1A1 (0.46) ALDH1A1CYP3A4TSHRLMNAALOX15
SCHEMBL11696873 0.74 ALDH1A1 (0.44) ALDH1A1CYP3A4TSHRLMNAALOX15
SCHEMBL11696880 0.74 ALDH1A1 (0.44) ALDH1A1CYP3A4TSHRLMNAALOX15
SCHEMBL435472 0.73 TSHR (0.52) CYP3A4TSHRACHE
SCHEMBL11851093 0.73 CTSA (0.37) ACHE
SCHEMBL435473 0.73 TSHR (0.52) CYP3A4TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4162155-A P-ACETAMIDOPHENOL AS STABILIZER FOR ISOOCTENYL 2,4-DICHLOROPHENOXY ACETATE HOWARD HALL & COMPANY (US) 1979-07-24 US disclosed
US-4062649-A Depletion indicator for controlled-release pesticide formulations SHELL OIL COMPANY (US) 1977-12-13 US disclosed
US-3961040-A PHOSPHORIC ACID ESTERS, SOLVENTS, ADSORBERS AIRWICK INDUSTRIES, INC. (US) 1976-06-01 US disclosed