Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645517 | 0.87 | LMNA (0.65) | LMNAEPHX1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL934969 | 0.86 | LMNA (0.49) | LMNAEPHX1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6782198 | 0.86 | MEN1 (0.45) | LMNAEPHX1PTGS2MEN1KMT2A | |
| SCHEMBL27599627 | 0.85 | KMT2A (0.44) | LMNAMEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL27599603 | 0.85 | MEN1 (0.44) | LMNAEPHX1PTGS2MEN1KMT2A | |
| SCHEMBL11562132 | 0.82 | CYP2C9 (0.59) | LMNAEPHX1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1565683 | 0.82 | LMNA (0.56) | LMNAMEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL28703755 | 0.82 | CYP2C9 (0.59) | LMNAEPHX1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14931890 | 0.82 | LMNA (0.51) | LMNAEPHX1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29283515 | 0.82 | LMNA (0.56) | LMNAMEN1KMT2ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157399-A | Benzo(B)thiophenes | PARCOR (FR) | 1979-06-05 | — | — | US | disclosed |