Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11563453 | 0.99 | MAPT (0.43) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11566075 | 0.79 | KDM4E (0.39) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8968478 | 0.75 | ACHE (0.43) | KDM4E | |
| SCHEMBL8969664 | 0.66 | KDM4E (0.30) | KDM4E | |
| SCHEMBL11333989 | 0.65 | MAPT (0.63) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8969165 | 0.64 | — | — | |
| SCHEMBL8969659 | 0.64 | — | — | |
| SCHEMBL8969712 | 0.62 | KDM4E (0.32) | KDM4E | |
| SCHEMBL8968378 | 0.60 | ACHE (0.43) | KDM4E | |
| SCHEMBL3434341 | 0.60 | MAPT (0.82) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134975-A | PYRIDO(1,2,-D)(1,4,6)BENZOXADIAZOCINES OR PYRIDO(1,2,-C)(1,3,5)BENZOXADIAZEPINES | E. R. SQUIBB & SONS, INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4062852-A | CNS STIMULANTS | E. R. SQUIBB & SONS, INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4003905-A | Diels-alder adducts of benzdiazepines | E. R. SQUIBB & SONS, INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3957806-A | STIMULANTS, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-05-18 | — | — | US | disclosed |