Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565081 | 0.82 | DPP4 (0.47) | DPP4KMT2AKDM4ECTSS | |
| SCHEMBL5019737 | 0.75 | POLB (0.48) | POLBTRPA1NPC1RAB9AMEN1 | |
| SCHEMBL21638024 | 0.74 | DPP4 (0.55) | DPP4POLBKDM4EALDH1A1NPSR1 | |
| SCHEMBL25967086 | 0.74 | DPP4 (0.55) | DPP4POLBKDM4EALDH1A1NPSR1 | |
| SCHEMBL21266464 | 0.72 | DPP4 (0.69) | DPP4CTSS | |
| SCHEMBL24567754 | 0.71 | POLB (0.45) | POLBTRPA1NPC1RAB9AMEN1 | |
| SCHEMBL18793674 | 0.71 | POLB (0.45) | POLBTRPA1NPC1RAB9AMEN1 | |
| SCHEMBL25583448 | 0.71 | MEN1 (0.46) | POLBTRPA1NPC1RAB9AMEN1 | |
| SCHEMBL25583447 | 0.71 | MEN1 (0.46) | POLBTRPA1NPC1RAB9AMEN1 | |
| SCHEMBL25583025 | 0.71 | MEN1 (0.46) | POLBTRPA1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156738-A | Ureidonitriles useful as antihypertensives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-05-29 | — | — | US | disclosed |