Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081589 | 0.72 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL16837304 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL10735324 | 0.71 | CYP4F2 (0.49) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL11735936 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL10744119 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL2845312 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL12686026 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL23182899 | 0.70 | ALDH1A1 (0.54) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL10739594 | 0.70 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA | |
| SCHEMBL13637085 | 0.70 | ALDH1A1 (0.54) | KDM4EALDH1A1SMN1; SMN2HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167575-A | BIOCIDES | ROHM AND HAAS COMPANY (US) | 1979-09-11 | — | — | US | disclosed |
| US-4053479-A | BIOCIDES | ROHM AND HAAS COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-3957808-A | BIOCIDES | ROHM AND HAAS COMPANY (US) | 1976-05-18 | — | — | US | disclosed |