Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 9/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11562718 | 0.98 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| SCHEMBL23292591 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| SCHEMBL11360870 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| SCHEMBL11560255 | 0.78 | ALDH1A1 (0.57) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL11561831 | 0.77 | ALDH1A1 (0.56) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| SCHEMBL11563269 | 0.75 | PTGS1 (0.56) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| SCHEMBL11561268 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL11565791 | 0.74 | PTGS1 (0.55) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| SCHEMBL23635873 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL11566891 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147794-A | Treatment of hypertension with thiadiazoles | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1979-04-03 | — | — | US | claimed |
| US-4147794-A | Treatment of hypertension with thiadiazoles | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1979-04-03 | — | — | US | disclosed |