Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8212968 | 0.97 | — | — | |
| Alcohol SCHEMBL11581601 | 0.94 | PAOX (0.39) | PAOXALDH1A1TSHRL3MBTL1ADH1B | |
| Diethanolamine SCHEMBL3675531 | 0.94 | PAOX (0.42) | PAOXALDH1A1TSHRL3MBTL1ADH1B | |
| SCHEMBL96357 | 0.94 | — | — | |
| SCHEMBL16343269 | 0.91 | PAOX (0.41) | PAOXALDH1A1TSHRL3MBTL1ADH1B | |
| Iodide SCHEMBL10379496 | 0.91 | — | — | |
| Bromide SCHEMBL29106634 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL27774021 | 0.91 | — | — | |
| Alcohol SCHEMBL11564413 | 0.91 | PAOX (0.44) | PAOXALDH1A1TSHRADH1BADH1A | |
| Diethanolamine SCHEMBL7696519 | 0.91 | ALDH1A1 (0.43) | ALDH1A1TSHRL3MBTL1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159964-A | Metal chelate catalyst and alkanolamine hydroxide on adsorptive support | UOP INC. (US) | 1979-07-03 | — | — | US | disclosed |
| US-4127474-A | Treating a petroleum distillate with an alkanolamine hydroxide and a supported oxidation catalyst impregnated with polynuclear aromatic sulfonic acid | UOP INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4124494-A | Treating a petroleum distillate with a supported metal phthalocyanine and an alkanolamine hydroxide | UOP INC. (US) | 1978-11-07 | — | — | US | disclosed |