Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 2/20 | 0.45 |
| ▸ | FPR2 | P25090 | 2/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407883 | 1.00 | KDM1A (0.50) | KDM1ASLC18A3MAOBMAOASIGMAR1 | |
| SCHEMBL8870050 | 1.00 | KDM1A (0.50) | KDM1ASLC18A3MAOBMAOASIGMAR1 | |
| SCHEMBL8471748 | 1.00 | KDM1A (0.50) | KDM1ASLC18A3MAOBMAOASIGMAR1 | |
| SCHEMBL8317532 | 1.00 | KDM1A (0.50) | KDM1ASLC18A3MAOBMAOASIGMAR1 | |
| SCHEMBL11565325 | 1.00 | KDM1A (0.50) | KDM1ASLC18A3MAOBMAOASIGMAR1 | |
| Hydrochloric Acid SCHEMBL11555721 | 0.98 | SLC18A3 (0.49) | KDM1ASLC18A3MAOBMAOASIGMAR1 | |
| Hydrochloric Acid SCHEMBL11555730 | 0.98 | SLC18A3 (0.49) | KDM1ASLC18A3MAOBMAOASIGMAR1 | |
| Hydrochloric Acid SCHEMBL442396 | 0.98 | SLC18A3 (0.49) | KDM1ASLC18A3MAOBMAOASIGMAR1 | |
| Bicarbonate SCHEMBL7443967 | 0.95 | MAPT (0.49) | KDM1ASLC18A3MAOBMAOASIGMAR1 | |
| SCHEMBL5923778 | 0.85 | SLC18A3 (0.54) | KDM1ASLC18A3MAOBMAOASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132710-A | DIURETICS, ANOREXICS, ANTIDEPRESSANTS, ANTICONVULSANTS, & ANTIHYPERTENSIVE AGENTS | AYERST, MCKENNA AND HARRISON, LTD. (CA) | 1979-01-02 | — | — | US | disclosed |