SCHEMBL407883

SCHEMBL407883

OC1CNCCC1c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.50
SLC18A3 Q16572 3/20 0.50
MAOB P27338 3/20 0.50
MAOA P21397 1/20 0.50
SIGMAR1 Q99720 1/20 0.48
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
FPR1 P21462 2/20 0.45
FPR2 P25090 2/20 0.45
CISD1 Q9NZ45 1/20 0.45
SLC6A2 P23975 1/20 0.45
HTR1B P28222 1/20 0.45
HTR2A P28223 1/20 0.45
SLC6A4 P31645 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8870050 1.00 KDM1A (0.50) KDM1ASLC18A3MAOBMAOASIGMAR1
SCHEMBL8471748 1.00 KDM1A (0.50) KDM1ASLC18A3MAOBMAOASIGMAR1
SCHEMBL11565322 1.00 KDM1A (0.50) KDM1ASLC18A3MAOBMAOASIGMAR1
SCHEMBL8317532 1.00 KDM1A (0.50) KDM1ASLC18A3MAOBMAOASIGMAR1
SCHEMBL11565325 1.00 KDM1A (0.50) KDM1ASLC18A3MAOBMAOASIGMAR1
Hydrochloric Acid SCHEMBL11555721 0.98 SLC18A3 (0.49) KDM1ASLC18A3MAOBMAOASIGMAR1
Hydrochloric Acid SCHEMBL11555730 0.98 SLC18A3 (0.49) KDM1ASLC18A3MAOBMAOASIGMAR1
Hydrochloric Acid SCHEMBL442396 0.98 SLC18A3 (0.49) KDM1ASLC18A3MAOBMAOASIGMAR1
Bicarbonate SCHEMBL7443967 0.95 MAPT (0.49) KDM1ASLC18A3MAOBMAOASIGMAR1
SCHEMBL5923778 0.85 SLC18A3 (0.54) KDM1ASLC18A3MAOBMAOASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11261282-B2 PEO-PPO-PEO triblock bipolymers, with amphoteric endings, as demulsifying agents for heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2022-03-01 US claimed
US-20200347173-A1 PEO-PPO-PEO TRIBLOCK BIPOLYMERS, WITH AMPHOTERIC ENDINGS, AS DEMULSIFYING AGENTS FOR HEAVY CRUDE OILS INSTITUTO MEXICANO DEL PETROLEO (MX) 2020-11-05 US claimed
US-10125226-B2 Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2018-11-13 US claimed
US-20140364566-A1 SCALE-UP PROCESS OF BIFUNCTIONALIZED TRIBLOCK COPOLYMERS WITH SECONDARY AND TERTIARY AMINES, WITH APPLICATION IN DEWATERING AND DESALTING OF HEAVY CRUDE OILS INSTITUTO MEXICANO DEL PETROLEO (MX) 2014-12-11 US claimed
CN-116909100-B Photosensitive polyimide precursor composition 深圳先进电子材料国际创新研究院 2024-03-19 CN disclosed
CN-116909100-A Photosensitive polyimide precursor composition 深圳先进电子材料国际创新研究院 2023-10-20 CN disclosed
US-10125226-B2 Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2018-11-13 US disclosed
US-20170313949-A1 DEHYDRATING AND DESALTING COMPOSITIONS OF CRUDE OILS, USING TRIBLOCK COPOLYMERS ALPHA,OMEGA-BIFUNCTIONALIZED WITH AMINES MEXICANO INST PETROL (MX) 2017-11-02 US disclosed
US-9745521-B2 Dehydrating and desalting compositions of crude oils, using triblock copolymers α,ω-bifunctionalized with amines INSTITUTO MEXICANO DEL PETROLEO (MX) 2017-08-29 US disclosed
US-9650577-B2 Synergistic formulations of functionalized copolymers and ionic liquids for dehydrated and desalted of medium, heavy and extra heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2017-05-16 US disclosed
US-9587182-B2 Synergistic formulations of functionalized copolymers and ionic liquids for dehydrated and desalted of medium, heavy and extra heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2017-03-07 US disclosed
US-9518231-B2 Demulsifying and dehydrating formulations for heavy crude oils based on block copolymers bifunctionalized with amines INSTITUTO MEXICANO DEL PETROLEO (MX) 2016-12-13 US disclosed
EP-0863875-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1998-09-16 EP disclosed
EP-0833637-A4 ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST MERCK & CO INC (US) 1998-07-08 EP disclosed
EP-0833637-A1 ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST Merck & Co., Inc. (US) 1998-04-08 EP disclosed
US-5654299-A TREATING RESPIRATORY SYSTEM DISORDER (I.E. ASTHMA) WITH NEUROKININ 2 RECEPTOR ANTAGONIST ZENECA LIMITED (GB) 1997-08-05 US disclosed
WO-1997009311-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1997-03-13 WO disclosed
WO-1996040136-A1 ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST MERCK & CO., INC. (US) 1996-12-19 WO disclosed
CN-1098094-A The heterocycle that aryl replaces ZENECA LTD (GB) 1995-02-01 CN disclosed
US-4132710-A DIURETICS, ANOREXICS, ANTIDEPRESSANTS, ANTICONVULSANTS, & ANTIHYPERTENSIVE AGENTS AYERST, MCKENNA AND HARRISON, LTD. (CA) 1979-01-02 US disclosed