Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671577 | 0.84 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL6468101 | 0.84 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL5362727 | 0.81 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL263217 | 0.81 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL1496589 | 0.81 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL5362724 | 0.81 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL16180345 | 0.81 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL27514088 | 0.79 | KMT2A (0.51) | KMT2AMEN1SMN1; SMN2GAAATM | |
| SCHEMBL9120301 | 0.78 | KDM4E (0.58) | KMT2AMEN1SMN1; SMN2LMNAMAPT | |
| SCHEMBL20379129 | 0.78 | CYP1A2 (0.37) | SMN1; SMN2LMNACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134975-A | PYRIDO(1,2,-D)(1,4,6)BENZOXADIAZOCINES OR PYRIDO(1,2,-C)(1,3,5)BENZOXADIAZEPINES | E. R. SQUIBB & SONS, INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-3965101-A | CNS STIMULANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3957806-A | STIMULANTS, MUSCLE RELAXANTS | E. R. SQUIBB & SONS, INC. (US) | 1976-05-18 | — | — | US | disclosed |