Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.77 |
| ▸ | CNR2 | P34972 | 1/20 | 0.68 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614146 | 0.90 | PTGS2 (0.83) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL11563404 | 0.89 | PTGS2 (0.83) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL12989547 | 0.88 | PTGS2 (0.77) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL11568267 | 0.86 | PTGS2 (0.79) | PTGS2CNR2AKR1C3HTR1APKM | |
| Pimetacin SCHEMBL287157 | 0.86 | PTGS2 (0.71) | PTGS2CNR2AKR1C3PTGS1GLO1 | |
| SCHEMBL8728498 | 0.84 | PTGS2 (0.71) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL4549122 | 0.84 | PTGS2 (1.00) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL29855593 | 0.83 | PTGS2 (0.86) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL12988768 | 0.83 | PTGS2 (0.86) | PTGS2CNR2AKR1C3HTR1APKM | |
| SCHEMBL31263060 | 0.82 | PTGS2 (0.75) | PTGS2CNR2AKR1C3HTR1APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165428-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTIPYRETICS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1979-08-21 | — | — | US | disclosed |