Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561754 | 0.89 | HTR2A (0.53) | MCL1CYP1A2CYP3A4HTR2APPARA | |
| SCHEMBL11566652 | 0.87 | PPARA (0.49) | CYP1A2CYP3A4HTR2APPARAABCB11 | |
| SCHEMBL11598181 | 0.76 | MCL1 (0.47) | MCL1CYP1A2CYP3A4PPARAKMT2A | |
| SCHEMBL11563901 | 0.76 | PPARA (0.45) | CYP1A2CYP3A4HTR2APPARAABCB11 | |
| SCHEMBL11562523 | 0.73 | PPARA (0.43) | CYP1A2CYP3A4HTR2APPARAABCB11 | |
| SCHEMBL10599282 | 0.73 | HTR2A (0.54) | MCL1CYP1A2HTR2AKMT2AMEN1 | |
| SCHEMBL1820711 | 0.73 | MCL1 (0.43) | MCL1PPARAKMT2AMEN1MAPT | |
| SCHEMBL11568731 | 0.73 | PPARA (0.60) | CYP1A2CYP3A4HTR2APPARAABCB11 | |
| SCHEMBL1824799 | 0.72 | MCL1 (0.45) | MCL1PPARAKMT2AMEN1MAPT | |
| SCHEMBL11597273 | 0.72 | KMT2A (0.46) | CYP1A2CYP3A4HTR2APPARAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |