Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | FABP2 | P12104 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566652 | 0.87 | PPARA (0.49) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11638260 | 0.85 | PPARA (0.60) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11562523 | 0.81 | PPARA (0.43) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11597273 | 0.79 | KMT2A (0.46) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL5389836 | 0.77 | PPARG (0.50) | PPARAMAPTMEN1KMT2APPARG | |
| SCHEMBL11565501 | 0.76 | MCL1 (0.40) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11537001 | 0.75 | PPARA (0.81) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11539959 | 0.75 | PPARA (0.60) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL2121452 | 0.74 | PPARA (0.68) | PPARACYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL11274148 | 0.72 | PPARA (0.56) | PPARACYP1A2CYP3A4CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4125729-A | Hypolipemic α-aryloxy para substituted phenyl acetic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |