Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | NT5E | P21589 | 3/20 | 0.50 |
| ▸ | CASP6 | P55212 | 5/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565609 | 0.99 | APEX1 (0.59) | APEX1NT5ECASP6NSD2DUSP3 | |
| SCHEMBL11426261 | 0.91 | APEX1 (0.47) | APEX1NT5ECASP6NSD2DUSP3 | |
| SCHEMBL11151522 | 0.91 | APEX1 (0.47) | APEX1NT5ECASP6NSD2DUSP3 | |
| SCHEMBL11137099 | 0.90 | APEX1 (0.51) | APEX1NT5ECASP6NSD2DUSP3 | |
| SCHEMBL11426244 | 0.89 | APEX1 (0.46) | APEX1NT5ECASP6NSD2DUSP3 | |
| SCHEMBL11137091 | 0.89 | APEX1 (0.50) | APEX1NT5ECASP6NSD2DUSP3 | |
| SCHEMBL11135640 | 0.87 | APEX1 (0.59) | APEX1NT5ECASP6NSD2DUSP3 | |
| SCHEMBL9822611 | 0.87 | APEX1 (0.59) | APEX1NT5ECASP6NSD2DUSP3 | |
| SCHEMBL11589837 | 0.87 | APEX1 (0.59) | APEX1NT5ECASP6NSD2DUSP3 | |
| SCHEMBL11154448 | 0.85 | CASP6 (0.46) | APEX1NT5ECASP6NSD2DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177209-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-04 | — | — | US | disclosed |
| US-4129590-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |