Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106972 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL16703930 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL2629347 | 0.76 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL16703928 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| Hydrochloric Acid SCHEMBL18131819 | 0.74 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL16698703 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL16699478 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL19781551 | 0.73 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL18421576 | 0.72 | NPC1 (0.65) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL2625578 | 0.72 | NPC1 (0.57) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166123-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1979-08-28 | — | — | US | disclosed |