Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.64 |
| ▸ | PTPRC | P08575 | 5/20 | 0.59 |
| ▸ | PTPRG | P23470 | 5/20 | 0.59 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | RXRB | P28702 | 2/20 | 0.50 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567962 | 0.87 | PTPRG (0.51) | ARMRGPRX4PTPRCPTPRGKMT2A | |
| SCHEMBL13802463 | 0.86 | PTPRG (0.70) | ARMRGPRX4PTPRCPTPRGKMT2A | |
| SCHEMBL11568053 | 0.83 | PTPRC (0.52) | ARMRGPRX4PTPRCPTPRGRXRA | |
| SCHEMBL11568611 | 0.82 | CYP1A2 (0.53) | ARMRGPRX4SMN1; SMN2TAS2R14NPC1 | |
| SCHEMBL693069 | 0.81 | RXRA (0.57) | ARMRGPRX4PTPRCPTPRGRXRA | |
| SCHEMBL11822185 | 0.81 | PTPRC (0.55) | ARMRGPRX4PTPRCPTPRGKMT2A | |
| SCHEMBL13802466 | 0.80 | MRGPRX4 (0.63) | ARMRGPRX4PTPRCPTPRGRXRA | |
| SCHEMBL22469767 | 0.78 | MRGPRX4 (1.00) | ARMRGPRX4PTPRCPTPRGNR4A2 | |
| SCHEMBL31568435 | 0.78 | MRGPRX4 (1.00) | ARMRGPRX4PTPRCPTPRGNR4A2 | |
| SCHEMBL7785082 | 0.75 | AR (0.64) | ARMRGPRX4PTPRCPTPRGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005055-A2 | 6,11-Dihydrodibenzo-thiepin-11-ones and their S-oxides, methods for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1979-10-31 | — | — | EP | disclosed |
| EP-0003422-A1 | Novel 4-(8X-6,11-dihydrodibenzo-(b,e)-thiepin-11-one-3-yl)-4-oxobutyric acids, methods of preparation, compositions and uses thereof | SYNTEX (U.S.A.) INC. (US) | 1979-08-08 | — | — | EP | disclosed |
| US-4130654-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, FRIBRINOLYTIC, MUSCLE RELAXANT | SYNTEX (U.S.A.) INC. (US) | 1978-12-19 | — | — | US | disclosed |