Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ANPEP | P15144 | 4/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380252 | 0.78 | ANPEP (0.56) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL28380251 | 0.78 | ANPEP (0.56) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL3537247 | 0.78 | KDM4E (0.53) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL27980382 | 0.76 | KDM4E (1.00) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL3393821 | 0.76 | KDM4E (0.74) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL3547551 | 0.76 | KDM4E (0.50) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL11768023 | 0.74 | KDM4E (0.48) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL30777623 | 0.74 | KDM4E (0.71) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL9830012 | 0.73 | EPHX1 (0.52) | SMN1; SMN2EPHX1NPC1RAB9AALDH1A1 | |
| SCHEMBL24715431 | 0.72 | KDM4E (0.68) | KDM4EANPEPERAP2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486061-A1 | COMPOSITIONS AND METHODS FOR THE TRANSPORT OF THERAPEUTIC AGENTS | Angiochem Inc. (CA) | 2012-08-15 | — | — | EP | disclosed |
| CN-100506811-C | (2S,3S) -3- [ [ (1S) -1-isobutoxymethyl-3-methylbutyl ] carbamoyl ] oxirane-2-carboxylate | NIPPON CHEMIPHAR CO (JP) | 2009-07-01 | — | — | CN | disclosed |
| CN-1809549-A | Salt of (2S,3S)-3-[[(1S)-1-isobutoxymethyl-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid | NIPPON CHEMIPHAR CO (JP) | 2006-07-26 | — | — | CN | disclosed |
| US-4144159-A | POLYGLYCIDYL ETHERS OF POLYPHENOLS, CHAIN EXTENSION, SALT FORMATION, QUATERNIZATION | PPG INDUSTRIES, INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4110287-A | Cataphoretic N-heterocyclic-containing resins for electrodeposition | PPG INDUSTRIES, INC. (US) | 1978-08-29 | — | — | US | disclosed |