Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 9/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561199 | 0.88 | CYP3A4 (0.47) | CYP3A4MAPTRXFP1THRBLMNA | |
| SCHEMBL11556588 | 0.88 | MAPT (0.38) | CYP3A4MAPTRXFP1THRBLMNA | |
| SCHEMBL11556973 | 0.84 | MAPT (0.36) | CYP3A4MAPTRXFP1THRBLMNA | |
| SCHEMBL11561427 | 0.84 | CYP3A4 (0.40) | CYP3A4MAPTRXFP1THRBLMNA | |
| SCHEMBL11560560 | 0.82 | MAPT (0.35) | CYP3A4MAPTRXFP1THRBLMNA | |
| SCHEMBL11561703 | 0.82 | MAPT (0.39) | CYP3A4MAPTRXFP1THRBLMNA | |
| SCHEMBL11559832 | 0.82 | KMT2A (0.40) | MAPTRXFP1LMNAKMT2AMEN1 | |
| SCHEMBL11561503 | 0.81 | MAPT (0.46) | CYP3A4MAPTTHRBLMNAKMT2A | |
| SCHEMBL11565451 | 0.80 | MEN1 (0.34) | CYP3A4MAPTRXFP1THRBLMNA | |
| SCHEMBL11560409 | 0.79 | CYP3A4 (0.50) | CYP3A4MAPTRXFP1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165229-A | SUBSTITUTED THIADIAZOL-2-YLUREA | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |