Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.71 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.71 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.57 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11562298 | 0.90 | OPRM1 (0.86) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| SCHEMBL11564513 | 0.87 | OPRM1 (0.71) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL11565333 | 0.87 | OPRM1 (0.73) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11569258 | 0.87 | OPRM1 (0.71) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| SCHEMBL11565122 | 0.85 | OPRM1 (0.80) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| SCHEMBL11568687 | 0.85 | OPRM1 (0.64) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| SCHEMBL11562163 | 0.84 | OPRM1 (0.68) | OPRM1OPRD1OPRK1CACNA1C | |
| SCHEMBL11563017 | 0.84 | OPRM1 (0.66) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11564667 | 0.83 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| Carfentanil SCHEMBL116222 | 0.83 | OPRM1 (1.00) | OPRM1OPRD1OPRK1CACNA1COPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |