Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.58 |
| ▸ | AR | P10275 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799584 | 0.80 | MAPT (0.54) | KIF11ARMAPTCA12CA9 | |
| SCHEMBL3495438 | 0.80 | CA12 (0.55) | KIF11ARMAPTCA12CA9 | |
| SCHEMBL29722177 | 0.80 | MAPT (0.54) | KIF11ARMAPTCA12CA9 | |
| SCHEMBL4595919 | 0.78 | AR (0.49) | KIF11AR | |
| SCHEMBL8872828 | 0.78 | MAPT (0.64) | KIF11MAPTCA12CA9HSD17B10 | |
| SCHEMBL2797928 | 0.76 | MAPT (0.54) | KIF11ARMAPTCA12CA9 | |
| SCHEMBL19785406 | 0.76 | KIF11 (0.81) | KIF11MAPTCA12CA9 | |
| SCHEMBL24721656 | 0.74 | KIF11 (0.55) | KIF11MAPTCA12CA9HSD17B10 | |
| SCHEMBL29483390 | 0.74 | TP53 (0.66) | CA12CA9 | |
| SCHEMBL4135726 | 0.74 | KIF11 (1.00) | KIF11ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166853-A | Antihypertensive 7-trifluoromethyl-4-aminoquinolones | THE UPJOHN COMPANY (US) | 1979-09-04 | — | — | US | disclosed |