Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 5/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905723 | 0.91 | APP (0.60) | NPC1RAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL3905720 | 0.91 | APP (0.60) | NPC1RAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL11561892 | 0.89 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL11829408 | 0.85 | APP (0.54) | NPC1RAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL12332412 | 0.85 | APP (0.56) | NPC1RAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL9858278 | 0.83 | HDAC6 (0.58) | NPC1RAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL11138585 | 0.83 | HDAC6 (0.58) | NPC1RAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL11561164 | 0.82 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL12639218 | 0.82 | MAPT (0.62) | NPC1RAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL4228077 | 0.81 | ESR1 (0.74) | NPC1RAB9ASMN1; SMN2TP53HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167628-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1979-09-11 | — | — | US | disclosed |