SCHEMBL3905720

SCHEMBL3905720

COc1ccc2nc(-c3ccc(/C=C/c4ccc(-c5nc6ccc(OC)cc6o5)cc4)cc3)oc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 0.60
HDAC6 Q9UBN7 2/20 0.58
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
TP53 P04637 5/20 0.55
MAPT P10636 5/20 0.50
LMNA P02545 3/20 0.50
ATP4A P20648 2/20 0.50
ATP4B P51164 2/20 0.50
GPR119 Q8TDV5 1/20 0.48
POLB P06746 1/20 0.48
CASP3 P42574 1/20 0.48
ALDH1A1 P00352 2/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
GLA P06280 1/20 0.48
GAA P10253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3905723 1.00 APP (0.60) APPHDAC6NPC1RAB9ASMN1; SMN2
SCHEMBL11829408 0.94 APP (0.54) APPHDAC6NPC1RAB9ASMN1; SMN2
SCHEMBL12332412 0.93 APP (0.56) APPHDAC6NPC1RAB9ASMN1; SMN2
SCHEMBL11566587 0.91 NPC1 (0.61) APPHDAC6NPC1RAB9ASMN1; SMN2
SCHEMBL11138585 0.89 HDAC6 (0.58) APPHDAC6NPC1RAB9ASMN1; SMN2
SCHEMBL9858278 0.89 HDAC6 (0.58) APPHDAC6NPC1RAB9ASMN1; SMN2
SCHEMBL11835372 0.85 TP53 (0.63) APPHDAC6NPC1RAB9ASMN1; SMN2
SCHEMBL28509208 0.84 APP (0.61) APPHDAC6NPC1RAB9ASMN1; SMN2
SCHEMBL29364586 0.84 APP (0.61) APPHDAC6NPC1RAB9ASMN1; SMN2
SCHEMBL16894043 0.84 APP (0.61) APPHDAC6NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293150-B2 Near-infrared absorbing material FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-8293150-B2 Near-infrared absorbing material FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-8021573-B2 Oxidized N,N*-[-(4-amino)diphenyl]-p-phenylenediamine derivatives or dimmonium salt; di-benzoxazole or chromene derivative as luminescent agent; light resistance, discoloration inhibition; optical filters and recording media FUJIFILM CORPORATION (JP) 2011-09-20 US disclosed
US-8021573-B2 Oxidized N,N*-[-(4-amino)diphenyl]-p-phenylenediamine derivatives or dimmonium salt; di-benzoxazole or chromene derivative as luminescent agent; light resistance, discoloration inhibition; optical filters and recording media FUJIFILM CORPORATION (JP) 2011-09-20 US disclosed
US-7875215-B2 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2011-01-25 US disclosed
US-7875215-B2 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2011-01-25 US disclosed
US-20100224839-A1 NEAR-INFRARED ABSORBING MATERIAL FUJIFILM CORPORATION (JP) 2010-09-09 US disclosed
US-20100224839-A1 NEAR-INFRARED ABSORBING MATERIAL FUJIFILM CORPORATION (JP) 2010-09-09 US disclosed
US-7615266-B2 Ink jet recording material EIKO EPSON CORPORATION (JP) 2009-11-10 US disclosed
US-20080291257-A1 INK JET RECORDING MATERIAL AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2008-11-27 US disclosed
EP-1705028-B1 Ink jet recording material SEIKO EPSON CORP (JP) 2008-05-21 EP disclosed
US-20080073626-A1 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080073626-A1 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080067479-A1 NEAR-INFRARED-ABSORBING MATERIAL AND NEAR-INFRARED-ABSORBING FILTER FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed
US-20080067479-A1 NEAR-INFRARED-ABSORBING MATERIAL AND NEAR-INFRARED-ABSORBING FILTER FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed
WO-2007111157-A1 NEAR INFRARED ABSORBING MATERIAL FUJIFILM CORPORATION (JP) 2007-10-04 WO disclosed
WO-2007111154-A1 NEAR-INFRARED ABSORBING MATERIAL FUJIFILM CORPORATION (JP) 2007-10-04 WO disclosed
US-20060216443-A1 Including fumed silica and layer including colloidal silica, and backcoat layer of polyurethane resin SEIKO EPSON CORPORATION 2006-09-28 US disclosed
EP-1705028-A1 Ink jet recording material SEIKO EPSON CORPORATION (JP) 2006-09-27 EP disclosed