Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558533 | 0.80 | DPP4 (0.43) | DPP4FAAHCES2ALDH1A1KMT2A | |
| SCHEMBL11563797 | 0.78 | NPSR1 (0.37) | DPP4MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL11565348 | 0.77 | TDP1 (0.37) | DPP4MAPTKMT2ATDP1NPSR1 | |
| SCHEMBL11560972 | 0.76 | DPP4 (0.40) | DPP4FAAHCES2ALDH1A1LMNA | |
| SCHEMBL11564013 | 0.76 | DPP4 (0.40) | DPP4MAPTLMNAKMT2ATDP1 | |
| SCHEMBL11558968 | 0.76 | CNR2 (0.37) | DPP4MAPTKMT2ATDP1NPSR1 | |
| SCHEMBL11563670 | 0.76 | DPP4 (0.48) | DPP4FAAHCES2ALDH1A1LMNA | |
| SCHEMBL11585145 | 0.76 | DPP4 (0.48) | DPP4MAPTLMNAKMT2ATDP1 | |
| SCHEMBL11561222 | 0.76 | DPP4 (0.48) | DPP4FAAHCES2ALDH1A1LMNA | |
| SCHEMBL11562253 | 0.76 | TDP1 (0.36) | DPP4MAPTALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148626-A | Herbicidal agents | THE BOOTS COMPANY LIMITED (GB) | 1979-04-10 | — | — | US | disclosed |