Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356400 | 0.83 | ALDH1A1 (0.53) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL7767263 | 0.83 | ALDH1A1 (0.53) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL7764064 | 0.83 | ALDH1A1 (0.53) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL22617489 | 0.81 | MAOB (0.53) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL22617255 | 0.81 | MAOB (0.53) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL7576590 | 0.79 | GAA (0.59) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL24496711 | 0.78 | MAOB (0.51) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL3399029 | 0.78 | MAOB (0.51) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL29586863 | 0.78 | MAOB (0.51) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL23662191 | 0.78 | MAOB (0.51) | MAOBADORA3ARKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178380-A | LIPOGENSIS INHIBITORS | SHELL OIL COMPANY (US) | 1979-12-11 | — | — | US | disclosed |