Chlorobenzene

Chlorobenzene

SCHEMBL11566975

CC(F)F.Clc1ccccc1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
CYP1A2 P05177 2/20 0.46
ADRB2 P07550 1/20 0.40
LMNA P02545 2/20 0.39
CYP2A6 P11509 1/20 0.39
IDO1 P14902 2/20 0.38
TDO2 P48775 2/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ORAI1 Q96D31 1/20 0.37
ORAI2 Q96SN7 1/20 0.37
ORAI3 Q9BRQ5 1/20 0.37
TRPV6 Q9H1D0 1/20 0.37
PNMT P11086 1/20 0.37
KCNH3 Q9ULD8 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A3 Q01959 2/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL28949858 0.85 TSHR (0.69) TSHRCYP1A2ADRB2LMNACYP2A6
Chlorobenzene SCHEMBL10430192 0.85 TSHR (0.69) TSHRCYP1A2ADRB2LMNACYP2A6
Chlorobenzene SCHEMBL29291039 0.84
Chlorobenzene SCHEMBL8816426 0.82 TSHR (0.65) TSHRCYP1A2ADRB2LMNACYP2A6
Chlorobenzene SCHEMBL10495324 0.82 TSHR (0.65) TSHRCYP1A2ADRB2LMNACYP2A6
Chlorobenzene SCHEMBL10408107 0.81
Chlorobenzene SCHEMBL3930673 0.81
SCHEMBL24715429 0.80 TSHR (1.00) TSHRCYP1A2LMNACYP2A6IDO1
Chlorobenzene SCHEMBL1568605 0.80 TSHR (1.00) TSHRCYP1A2LMNACYP2A6IDO1
Chlorobenzene SCHEMBL2168046 0.80 TSHR (1.00) TSHRCYP1A2LMNACYP2A6IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4173706-A REACTING WITH MOLYBDENUM HEXAFLUORIDE INSTITUTE NATIONAL DE RECHERCHE CHIMIQUE APPLIQUEE (FR) 1979-11-06 US disclosed