Chlorobenzene

Chlorobenzene

SCHEMBL2168046

Clc1ccccc1.Clc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 1.00
CYP1A2 P05177 2/20 0.62
CYP2A6 P11509 4/20 0.58
LMNA P02545 3/20 0.58
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
ORAI1 Q96D31 1/20 0.48
ORAI2 Q96SN7 1/20 0.48
ORAI3 Q9BRQ5 1/20 0.48
TRPV6 Q9H1D0 1/20 0.48
ALDH1A1 P00352 2/20 0.43
IDO1 P14902 3/20 0.42
TDO2 P48775 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
ALOX15 P16050 1/20 0.40
BBOX1 O75936 1/20 0.39
EHMT2 Q96KQ7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL1330516 1.00
Chlorobenzene SCHEMBL1339852 1.00
Chlorobenzene SCHEMBL1331798 1.00
Chlorobenzene SCHEMBL1568605 1.00 TSHR (1.00) TSHRCYP1A2CYP2A6LMNACES2
Chlorobenzene SCHEMBL11220629 1.00 TSHR (1.00) TSHRCYP1A2CYP2A6LMNACES2
Chlorobenzene SCHEMBL9721018 1.00 TSHR (1.00) TSHRCYP1A2CYP2A6LMNACES2
SCHEMBL24715429 1.00 TSHR (1.00) TSHRCYP1A2CYP2A6LMNACES2
Chlorobenzene SCHEMBL1330702 1.00
Chlorobenzene SCHEMBL2044 1.00
Chlorobenzene SCHEMBL1162346 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11306041-B2 Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2022-04-19 US disclosed
US-20210163377-A1 CATALYTIC SYNTHESIS OF SUPER LINEAR ALKENYL ARENES USING RHODIUM CATALYSTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2021-06-03 US disclosed
CN-110465291-A A kind of monatomic noble metal type catalyst Ru/Cr2O3And its preparation method and application UNIV TAIYUAN TECHNOLOGY 2019-11-19 CN disclosed
CN-107240643-B Bromo element adulterates methylamine lead iodine perovskite solar battery and preparation method thereof 太原理工大学 2019-11-05 CN disclosed
CN-106715518-B Conjugated polymer 默克专利有限公司 2019-10-25 CN disclosed
CN-110156965-A A kind of low band-gap conjugated polymer and the preparation method and application thereof containing cyclopentadienone and naphthalimide 湘潭大学 2019-08-23 CN disclosed
CN-109791987-A Organic semiconductor compound 默克专利有限公司 2019-05-21 CN disclosed
CN-109772385-A A kind of metal phosphide catalyst and its preparation method and application that carbon is self-supported 浙江工业大学 2019-05-21 CN disclosed
CN-108368265-A Thiadiazoles and pyridine polymers, its synthesis and application thereof 默克专利股份有限公司 2018-08-03 CN disclosed
CN-106397743-B A kind of application of water soluble fluorescent conjugated polymer in nitro-aromatic detection 齐鲁工业大学 2018-07-03 CN disclosed
CN-102666643-A Polymer compound, thin film containing the same, and ink composition SUMITOMO CHEMICAL CO 2012-09-12 CN disclosed
CN-1986610-B Hydrogenated nitrile rubber with narrow molecular weight distribution, a process for its preparation and its use LANXESS DEUTSCHLAND GMBH 2012-06-13 CN disclosed
US-7972551-B2 Method of producing solid body having depressed portions on its surface and method of producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2011-07-05 US disclosed
CN-1986610-A Hydrogenated nitrile rubber with narrow molecular weight distribution, a process for its preparation and its use LANXESS DEUTSCHLAND GMBH (DE) 2007-06-27 CN disclosed
CN-1244017-C Method for imprinting molecular-level pattern on surface JOHN C POLANYI (CA) 2006-03-01 CN disclosed
CN-1444609-A Graft Copolymerization of Polyolefins DU PONT (US) 2003-09-24 CN disclosed
US-6586148-B1 A photoconductive member with a supporting substrate, and thereover a first layer comprised of a mixture of a photogenerator component, a hole transport component, and an electron transport component; and thereover a second layer of XEROX CORPORATION 2003-07-01 US disclosed
CN-1285932-A Method for imprinting molecular-level pattern on surface JOHN C POLANYI (CA) 2001-02-28 CN disclosed
US-5021413-A Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them SANKYO COMPANY LIMITED (JP) 1991-06-04 US disclosed
US-4933245-A WEAR RESISTANCE, SAG-FREE COATINGS FUJI XEROX CO., LTD. (JP) 1990-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163377-A1 CATALYTIC SYNTHESIS OF SUPER LINEAR ALKENYL ARENES USING RHODIUM CATALYSTS MSMO1, CYP2E1, PNMT TSHR 3693/4885CYP1A2 18/4885CYP2A6 45/4885
US-11306041-B2 Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts MSMO1, CYP2E1, PNMT TSHR 3693/4885CYP1A2 18/4885CYP2A6 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.