Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866869 | 0.92 | CES1 (0.47) | CES1SRCPPARGPPARAELANE | |
| SCHEMBL5512518 | 0.86 | PPARG (0.49) | PPARGPPARAELANETSHRALDH1A1 | |
| SCHEMBL27474029 | 0.81 | CES1 (0.56) | CES1SRCELANETDP1TSHR | |
| SCHEMBL27817560 | 0.81 | PPARG (0.45) | PPARGPPARAELANETSHRALDH1A1 | |
| SCHEMBL2142613 | 0.81 | PPARG (0.48) | CES1SRCPPARGPPARAELANE | |
| SCHEMBL11512906 | 0.81 | CES1 (0.47) | CES1SRCPPARGELANETDP1 | |
| SCHEMBL27908747 | 0.79 | CES1 (0.46) | CES1SRCPPARGPPARAELANE | |
| SCHEMBL11513416 | 0.79 | SRC (0.50) | CES1SRCPPARGELANETDP1 | |
| SCHEMBL9736278 | 0.79 | MAPT (0.47) | PPARGPPARAALDH1A1HSD17B10MAPT | |
| SCHEMBL2588222 | 0.78 | PPARG (0.36) | PPARGPPARAELANEALDH1A1FABP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179515-A | HYPOLIPEMIC, HYPOCHOLESTEROLEMIC, CHOLAGOGIC | ORCHIMED S. A. (CH) | 1979-12-18 | — | — | US | disclosed |