SCHEMBL11512906

SCHEMBL11512906

CC(Oc1ccccc1)(Oc1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.47
SRC P12931 1/20 0.47
TSHR P16473 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 1/20 0.44
ELANE P08246 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MAPT P10636 1/20 0.43
CES2 O00748 2/20 0.41
PPARG P37231 3/20 0.41
AKR1C3 P42330 1/20 0.40
F2 P00734 1/20 0.40
LMNA P02545 1/20 0.40
ATM Q13315 1/20 0.40
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11512979 0.88 PPARA (0.57) CES1TSHRTDP1ALDH1A1ELANE
SCHEMBL2142613 0.84 PPARG (0.48) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL11866869 0.84 CES1 (0.47) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL11513416 0.82 SRC (0.50) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL1538043 0.81 PPARA (0.47) TSHRALDH1A1HSD17B10ELANEL3MBTL1
SCHEMBL11566993 0.81 CES1 (0.44) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL3661644 0.79 CES1 (0.60) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL11513547 0.79 L3MBTL1 (0.42) TSHRTDP1ALDH1A1HSD17B10ELANE
Water SCHEMBL28074674 0.79 PPARA (0.46) TSHRALDH1A1HSD17B10ELANEL3MBTL1
SCHEMBL10946881 0.78 PPARG (0.57) TSHRTDP1ALDH1A1ELANEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4147791-A 1-Substituted-1,2,4-triazole fungicidal compositions and methods for combatting fungi that infect or attack plants BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
US-4048318-A 1-Substituted-1,2,4-triazole fungicides BAYER AKTIENGESELLSCHAFT (DT) 1977-09-13 US disclosed